Paravertebral deep back muscles of girls with idiopathic scoliosis reveal expression of receptors for estrogens
نویسندگان
چکیده
Introduction Estrogens can influence skeletal muscles activity by stimulating angioand muscle-genesis. These hormones act through specific alpha and beta estrogen receptors (ER). Muscular tissue may be a target for estrogens, however there is no data on ER expression in paravertebral muscles in patients with idiopathic scoliosis (IS). During early adolescence the increase of estrogen serum level coincidences with the period of rapid scoliosis progression. The aim of the study was to investigate ER alpha expression in the paravertebral muscles of patients with IS.
منابع مشابه
Proline, glutamic acid, and leucine rich protein 1 (PELP1) expression in deep paravertebral muscles in idiopathic scoliosis girls
Objectives Estrogens and their receptors are postulated to be important factors in development of idiopathic scoliosis. Transcription functions of estrogen receptors are influenced by coregulators such as proline, glutamic acid, and leucine rich protein 1 (PELP1). Deep paravertebral muscles are potential elements participating in idiopathic scoliosis development. The aim of the present study wa...
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